Refractory Acute Myeloid Leukemia CD33 Positive | Acute Myelocytic Leukemia Relapse CD33 Positive | Status post Standard of Care | Curative treatment Lacking
Item
patients with cd33-positive acute myeloid leukemia, refractory or relapsed after standard treatment with no curative option available
boolean
C4528668 (UMLS CUI [1,1])
C4329511 (UMLS CUI [1,2])
C0023467 (UMLS CUI [2,1])
C0035020 (UMLS CUI [2,2])
C4329511 (UMLS CUI [2,3])
C0231290 (UMLS CUI [3,1])
C2936643 (UMLS CUI [3,2])
C1273390 (UMLS CUI [4,1])
C0332268 (UMLS CUI [4,2])
ECOG performance status
Item
ecog performance status 0 to 2
boolean
C1520224 (UMLS CUI [1])
Gemtuzumab ozogamicin | Mylotarg
Item
therapy with gemtuzumab ozogamicin (mylotarg) within 6 months prior to inclusion
boolean
C1533699 (UMLS CUI [1])
C0876099 (UMLS CUI [2])
Transplantation, Homologous
Item
allogenic transplantation within 6 months prior to inclusion
boolean
C0040739 (UMLS CUI [1])
Prior Therapy | Chemotherapy | Targeted Therapy | Therapeutic radiology procedure | Exception Hydroxyurea | Exception Leukapheresis
Item
prior therapy (chemotherapy, targeted agents, radiotherapy) within 3 weeks except for hydroxyurea and for leukophoresis
boolean
C1514463 (UMLS CUI [1])
C0392920 (UMLS CUI [2])
C2985566 (UMLS CUI [3])
C1522449 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C0020402 (UMLS CUI [5,2])
C1705847 (UMLS CUI [6,1])
C0023416 (UMLS CUI [6,2])
AVE9633
Item
previous treatment with ave9633
boolean
C3501972 (UMLS CUI [1])
Renal function Poor | Liver function Poor | Poor bone marrow function
Item
poor kidney, liver and bone marrow functions
boolean
C0232804 (UMLS CUI [1,1])
C0542537 (UMLS CUI [1,2])
C0232741 (UMLS CUI [2,1])
C0542537 (UMLS CUI [2,2])
C1389329 (UMLS CUI [3])
Disease Serious Interferes with Patient safety | Comorbidity Serious Interferes with Patient safety | Disease Serious Interferes with Protocol Compliance | Comorbidity Serious Interferes with Protocol Compliance
Item
any serious active disease or co-morbid condition, which in the opinion of the principle investigator, will interfere with the safety or with compliance with the study
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C1113679 (UMLS CUI [1,4])
C0009488 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C1113679 (UMLS CUI [2,4])
C0012634 (UMLS CUI [3,1])
C0205404 (UMLS CUI [3,2])
C0521102 (UMLS CUI [3,3])
C0525058 (UMLS CUI [3,4])
C0009488 (UMLS CUI [4,1])
C0205404 (UMLS CUI [4,2])
C0521102 (UMLS CUI [4,3])
C0525058 (UMLS CUI [4,4])
Pregnancy | Breast Feeding
Item
pregnant or breast-feeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Females & males of reproductive potential Contraceptive methods Absent
Item
patient with reproductive potential without effective birth control methods
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Eligibility Criteria Additional
Item
the above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
boolean
C1516637 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])